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Pro-Mag™ PLM-2000 isolates total RNA using silica-coated magnetic beads for isothermal amplification, RT-PCR, and real-time PCR workflows. 100 preparations per kit. Research use only.
Silica-coated magnetic beads bind RNA in solution without membrane columns. Optional PLM-2001/2002/2003 racks provide magnetic separation during purification. The current instruction manual still requires centrifugation during sample clarification.
Confirmed — product description, pro-lab-direct.comThe PLM-2000 instruction manual lists isothermal amplification as an intended molecular-biology application. Laboratories must validate performance with their specific assay, instrument, and sample matrix.
Confirmed — product page: "validated applications: LAMP"The protocol uses magnetic separation during binding, washing, and elution. The current instruction manual also requires centrifugation during sample clarification.
Claimed — manufacturer: "total RNA within minutes" (pro-lab-direct.com)RNases are everywhere. Even trace contamination destroys RNA templates. Pro-Mag™ buffers undergo RNase-free quality control testing on every lot before release — protecting your extractions at the reagent manufacturing level.
Confirmed — product page: "RNase-free QC on all buffer components"Pro-Mag™ PLM-2000 uses silica-coated magnetic beads and is intended for molecular-biology workflows including isothermal amplification. Validate performance with the specific assay, instrument, and sample matrix before use.
Pro-Mag™ PLM-2000 eliminates spin-column membranes. Silica magnetic beads capture RNA in solution; use the optional magnetic rack (PLM-2001/2002/2003) to hold the beads while wash buffer is removed. The instruction manual requires a centrifugation step during sample clarification before magnetic purification.
Genie II / Genie III / Genie HT
Real-time LAMP detection platforms available from the same distributor. Validate PLM-2000 eluate with the specific Genie® assay and instrument before use.
View Genie® Instruments →
ISO-004 — Optigene
Optigene's isothermal amplification mastermix. Compatibility with PLM-2000 eluate requires laboratory validation for the specific assay workflow.
View Mastermix →
PLD001 / PLD010
Single-use inoculating loops for specimen handling and transfer. Required for workflows where sample transfer to extraction tube is part of the protocol.
View Pro-Loops™ →| Specification | Value | Source |
|---|---|---|
| Catalog Number | PLM-2000 | pro-lab-direct.com product page [Confirmed] |
| Kit Format | Silica-coated magnetic beads + optimized RNase-free buffers | pro-lab-direct.com [Confirmed] |
| Kit Contents (per kit) | Lysis Buffer 110 mL · Binding Beads 2 mL · Wash Buffer 110 mL · Elution Buffer 5 mL | IFU PLM-2000 Rev. 2 (25 Apr 2017) [Confirmed] |
| Preparations per Kit | 100 preparations | pro-lab-direct.com [Confirmed] |
| Storage Conditions | Lysis Buffer — room temperature. Binding Beads, Wash Buffer, Elution Buffer — 2–8°C. Do not freeze. | IFU PLM-2000 Rev. 2 (25 Apr 2017) [Confirmed] |
| Shelf Life | Stable for at least 6 months under stated conditions | IFU PLM-2000 Rev. 2 (25 Apr 2017) [Confirmed] |
| Buffer Preservative | Sodium azide 0.05% (do not dispose unused reagent down drain — reacts with plumbing metals) | IFU PLM-2000 Rev. 2 (25 Apr 2017) [Confirmed] |
| Validated Applications | LAMP (Loop Mediated Isothermal Amplification), Real-time PCR (qPCR), Reverse Transcription-PCR (RT-PCR) | pro-lab-direct.com [Confirmed] |
| QC Standard | RNase-free QC — all buffer components tested per lot before release | pro-lab-direct.com [Confirmed] |
| Throughput | Scalable — flexible sample processing for low- and high-throughput labs | pro-lab-direct.com [Claimed] |
| Protocol | Quick, easy protocol — lysis, bead binding, magnetic wash, elution | pro-lab-direct.com [Claimed] |
| Centrifuge Required | Yes — current instruction manual requires centrifugation during sample clarification; magnetic racks are used during purification | Product format [Confirmed] |
| Accessory SKUs | PLM-2001, PLM-2002, PLM-2003 (optional magnetic separator racks) | pro-lab-direct.com [Confirmed] |
| Regulatory Classification | For Research Use Only — Not intended for the diagnosis, prevention, or treatment of disease | IFU PLM-2000 ver-20200514 [Confirmed] |
| Manufacturing Standard | Research Use Only — not intended for diagnosis, prevention, or treatment | Corroborated — Pro-Lab corporate standard |
| Pricing | Quote-based — contact Pro-Lab Direct for institutional pricing | pro-lab-direct.com [Confirmed — no price listed] |
| Product Page | pro-lab-direct.com/product-p/plm-2000.htm | Volusion product catalog |
Storage: Lysis Buffer — room temperature. Binding Beads, Wash Buffer, Elution Buffer — 2–8°C. Do not freeze. Stable for at least 6 months under stated conditions. Buffers contain sodium azide (0.05%) as preservative — do not dispose down the drain. Source: PLM-2000 IFU, Rev. 2 (25 Apr 2017).
The current instruction manual describes processing samples in solution and frozen or fibrous samples, but it does not publish a validated specimen-type list. Contact Pro-Lab technical support for sample-specific guidance and validate the chosen matrix before use.
Pro-Mag™ PLM-2000 uses magnetic separation during purification, while the current instruction manual requires centrifugation during sample clarification. Contact Pro-Lab technical support for protocol timing data specific to your sample type and throughput requirements.
Pro-Mag™ PLM-2000 is intended for molecular-biology workflows including isothermal amplification. Compatibility with specific Optigene Genie® instruments is not established in the current PLM-2000 instruction manual. Validate the extraction, assay, and instrument combination before use.
Pro-Mag™ PLM-2000 binds RNA to silica-coated beads suspended in solution, then uses a magnetic separator rack to hold the beads while wash buffers are removed. This avoids spin-column membranes, but the instruction manual still requires centrifugation during sample clarification.
Pro-Mag™ PLM-2000 includes RNase-free quality control testing on all buffer components — every buffer lot is tested for RNase activity before release. RNases are ubiquitous environmental contaminants that degrade RNA during and after extraction, leading to failed amplification and false-negative results. Lot-level RNase QC is a manufacturing control that protects RNA integrity at the source — before the kit reaches your lab. This is a confirmed quality specification stated on the Pro-Mag product page.
The PLM-2001, PLM-2002, and PLM-2003 are optional magnetic separator racks used to hold beads against the tube wall during purification. The current instruction manual still requires centrifugation during sample clarification. Contact Pro-Lab technical support before substituting another magnetic separator.
The PLM-2000 instruction manual lists isothermal amplification as an intended application. Extraction performance, inhibitor tolerance, and compatibility must be validated for each assay and sample matrix.
Per IFU PLM-2000 Rev. 2 (25 Apr 2017): the Lysis Buffer is stored at room temperature; Binding Beads, Wash Buffer, and Elution Buffer are stored at 2–8°C. Do not freeze any component. The kit is stable for at least 6 months under these conditions. Buffers contain sodium azide 0.05% as preservative — do not dispose of unused reagent down drains (sodium azide reacts with metals in plumbing). For pricing and ordering, use the Request Quote button on this page or call Pro-Lab Direct at 512-832-9145.
PLM-2000 — 100 preps. Silica magnetic beads. RNase-free QC. Quote-based pricing.
Add PLM-2000 to your order. Include magnetic racks (PLM-2001/2002/2003) for magnetic separation during purification.
Ordering 200+ preps per month? Request volume pricing for PLM-2000 and magnetic rack accessories.
Speak with a Pro-Lab molecular diagnostics specialist about LAMP validation, protocol transfer, or documentation requirements.
Request the current PLM-2000 instruction manual and ask which controlled lot documents are available.
Get the LAMP Extraction Protocol Guide — magnetic bead vs. column comparison for isothermal amplification workflows. Approximately 2–4 emails/month from Pro-Lab Direct.
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